教授

邱相君
2016-09-09 23:21  


邱相君,男,19714月出生,硕士,教授。河南科技大学医学院医学机能学实验教学中心主任,中国药理学会会员、河南省药理学会常务理事、河南省抗癌协会纳米专业委员会委员、河南省抗癌协会肿瘤精准医学专业委员会委员。

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【教育和工作经历】

1990.9-1995.6   河南医科大学攻读学士学位

1995.7-2001.8   中铁十五局集团工作

2001.9-2004.6   温州医学院攻读硕士学位

2004.7-至今      河南科技大学工作

【成果】

1.        The Effects of(+)-Gossypol on 11β-HSD and the Concentration of Corticosteroneand Dehydrocorticosterone in Mice Serum and Tissues河南省优秀论文二等奖,2013

2.        盐酸曲美他嗪片的人体生物等效性研究,洛阳市科技进步二等奖2010

3.        疑似非淋菌尿道炎儿童泌尿生殖道支原体衣原体感染状况及耐药性研究,洛阳市科技进步二等奖,2010

4.       盐酸曲美他嗪片的人体生物等效性研究,河南省优秀论文二等奖,2010

5.       超高液相色谱-质谱同时检测人血浆对乙酰氨基酚和双氢可待因及其应用,河南省科技厅科技成果鉴定,国内领先,2015

6.        UPLC-MS同时检测人血浆厄贝沙坦和氢氯噻嗪及其生物等效性研究,河南省科技厅科技成果鉴定,国内领先,2014

7.        HPLC法测定大鼠肝微粒体CYP2C9CYP3A酶活性以及芹菜素对其影响,河南省科技厅科技成果鉴定,国内领先,2013

8.        一种治疗鼻炎、鼻窦炎的中药组合物及其制备方法,201110186729.9,已授权,2012

9.        一种治疗风湿类关节炎的中药,201110414640.3,已授权,2014

10.    一种治疗手指麻木的中药组合物,201210270757.32014

【在研项目】

1.        厄洛替尼和抗消化性溃疡药的相互作用及其机制研究,河南省科技攻关项目152102310309,洛阳市科技计划医疗卫生项目1503001A-12015

2.        帕唑帕尼和索拉菲尼的药代动力学和相互作用研究,企业委托,2015

【发表论文】

1.      Xiangjun Qiu, Jian-long Zhao, Cong Hao, Canli Yuan, NuanTian, Zhi-sheng Xu, Ruan-min Zou, Simultaneous determination of mangiferin andneomangiferin in rat plasma by UPLC–MS/MS and its application forpharmacokinetic study, Journal of Pharmaceutical and Biomedical Analysis2016124138-142

2.      Yuniao Zhang, Wei Sun,Yongyang Pan, Tao Li, Xiaojie Yang, Renai Xu, Xiangjun Qiu, Pharmacokineticschanges of ivabradine and N-desmethylivabradine after oral administration withpuerarin in rats, International Journal of Clinical and Experiment Medicine,2016, 9(5):8369-8374(通讯作者)

3.      Hongchang YUAN,Jianfang FENG, Dongtao ZHANG, Jie ZHANG, Yajun WANG,  Xiangjun QIU,Development and Validation of UPLC-MS/MS Method for the Determination ofAndrographolide in Human Plasma, Latin American Journal of Pharmacy2015346):1205-1210(通讯作者)

4.      Xiangjun Qiu, Dan Lou, Ding Su, Zebin Liu, Pengtao Gao,Nan-sheng Zhang, Simultaneous determination of acetaminophen and dihydrocodeinein human plasma by UPLC–MS/MS: Its pharmacokinetic application, Journal of ChromatographyB201599291-95

5.      Xiangjun Qiu, Hong-wei Wang, Ye Yuana, Ying-fei Wang,Ming Sun, Xue-sun Huang, An UPLCMS/MS methodfor the analysis of glimepiride and fluoxetine in human plasma. Journal of ChromatographyB201598016-19

6.      Xiangjun Qiu, Shuang-li Zheng, Yingfei Wang, Rong Wang,Lei Ye, A rapid and simple UPLC-MS/MS method for determination of glipizide inhuman plasma and its application to bioequivalence studyJournal of Chromatography Science2015531):85-89

7.      Xiangjun Qiu, Jianlong Zhao, Zhe Wang, Zhisheng Xu,Ren-ai Xu, Simultaneous determination of Bosentan and Glimepiride in humanplasma by ultra performance liquid chromatography tandem mass spectrometry and itsapplication to a pharmacokinetic study. Journal of Pharmaceutical andBiomedical Analysis201495207-212

8.      Xiangjun Qiu, Zhe Wang, Bing Wang, Hui Zhan, XiaofengPan, Ren-ai Xu, Simultaneous determination of irbesartan and hydrochlorothiazidein human plasma by ultra high performance liquid chromatography tandem massspectrometry and its application to a bioequivalence studyJournal of Chromatography B2014957110-115

9.      Xiangjun Qiu, Shuang-li ZHENG,Ying-fei WANG, Rong WANG, Lei YE, Rapid and Sensitive UPLC-MS/MS Method for the Determinationof Domperidone in Human Plasma and its Application to Pharmacokinetic StudyDrug Research2014646):330-334

10.  Xiangjun Qiu, Jijun Song, HongchangYuan, Yi Hou, Xiaofeng Pan, Ren-ai Xu, Evaluation of CYP2C9 activity in rats: use oftolbutamide alone and in combined with bupropionIranianJournal of Pharmaceutical Research2014132):635-639

11.  Xiangjun QIU, Ai-li FEI, Zhisheng XU, Xiaoxiang DU,Haiyan ZHU, Ren-ai XU, Determination of Tolbutamide and Hydroxytolbutamide byLCMS/MS in Rat and its Application toAssessment of CYP2C9 ActivityLatin American Journal ofPharmacy2012317):999-1004

12.  Xiangjun QIU, Ren-ai XU, Yuancai ZHENG, Haichao ZHAN,Zhe WANG, Lufeng HU, Determination of Pantoprazole in Rat Plasma by LCMS/MS and its Application to PharmacokineticsLatin American Journal of Pharmacy2012315):653-8

13.  Xiangjun QIU, Wanshu LI, Junwei LI 1, Mengmeng WANG,Jia WANG, Lianguo CHEN, Wei SUN, Likang ZHANG, Congcong WEN, Renshan GE, GuoxinHU, The Effects of (+)-Gossypol on 11β-HSD and theConcentration of Corticosterone and Dehydrocorticosterone in Mice Serum andTissuesLatin American Journal of Pharmacy2012314):615-9

14.  反相高效液相色谱法检测人血浆伊马替尼的浓度,中国临床药理学杂志,20132910):777-779

15.  高效液相色谱法测定大鼠肝微粒体CYP3A酶的活性,中国临床药理学杂志,20122811):852-854

16.  盐酸二甲双胍篇在健康人体的生物等效性,中国临床药理学杂志,2012284):278-280

17.  厄贝沙坦氢氯噻嗪胶囊在健康人体的生物等效性,中国临床药理学杂志,20112711):851-855

18.  氨酚双氢可待因胶囊在健康人体的生物等效性,中国临床药理学杂志,2011272):121-124

19.  反相高效液相色谱法检测兔血浆胞磷胆碱的浓度,中国药师,2011,144):488-490(通讯作者)

20.  单硝酸异山梨酯滴丸的人体生物等效性,中国医院药学杂志,20093015):1292-1295

【联系方式】

工作单位:河南科技大学医学院

电子信箱:lyxiangjun@126.com

   话:13698882699

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